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Hematology II
WELCOME LETTER TO STUDENTS
It is with great happiness I welcome the third year Medical Lab Science students to this advanced course to the science of blood “Hematology”. As having just passed your second year, you are well acquainted with basic hematology I (MLT 205). The previous course was very important in order to understand and follow the diseases of blood, which will be thoroughly explained in this one. With successful passing of this course, you should be able to deal with any hematological problem in the future whether normal or pathological. I wish you a pleasant semester of learning.
COURSE DESCRIPTION
This course is dedicated mainly to the WBC abnormalities (both benign and malignant). The lectures discuss in great detail all of the malignant diseases involving all types of WBC. That is, acute and chronic leukemia of lymphoid and non-lymphoid (myeloid) origin. Also discussed in great detail, are the lymphomas, and plasma cell dyscrasis. Finally the later lectures discuss all of the benign (non-malignant) WBC disorders.
All lectures pay great attention toward the pathophysiology of the diseases, their symptoms, methods of detection (with the greatest emphasis paid towards the laboratory findings and their significance), and finally conclude with their treatments. Two of the three lectures given per week are allocated for this section of the course (i.e., WBC abnormalities). One of the two practical sessions is allocated cover all the practical material pertaining to the WBC abnormalities, where all of the hematological tests significant to the nature of the subject, are demonstrated and practiced. These include differential counts of leukemic samples, Immunophenotyping (when available), and special stains (cytochemistry) such as NAP score, Esterase’s, Peroxidase, Periodic Acid Schiff (PAS), Acid Phosphatase, etc.
Con-currently, the third lecture of the three given per week is allocated for “Hemostasis and Coagulation” subject. This part of the course is dedicated entirely to the mechanism involved in coagulation and hemostasis including the coagulation factors, the methods of activation (intrinsic and extrinsic pathways), the Fibrinolytic system, and platelets structure, and function. The later parts of this section concentrate on the pathological states of coagulation leading to clotting problems such hemophilia, DIC, Primary Fibrinolysis, etc. The remaining practical session (per week) is dedicated to hemostasis and coagulation methodologies such as PT, PTT, TT, bleeding time, mixing studies, factor assays, platelets aggregation and adhesion studies, etc.
Clarification
Previous to this year “Hemostasis & Coagulation” section used to be separately taught on its own in a course properly named “Hemostasis & Coagulation”. The course counted for two credit hours consisting of one 50-minute lecture, one 50-minute tutorial, and a 2-hour practical lab session. Similarly, “Hematology II” used to be a course dedicated entirely to the WBC abnormalities. Hematology II used to be a three hour credit course consisting of 2 50-minute lectures, one 50-minute tutorial, and one 2-hour practical lab session.
This year the two subjects were merged together and given the name of “Hematology II”. However, the amount of total credit hours, and the material covered, in both subjects have not been altered due to the emergence.
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